Proton pump inhibitors (PPIs) are a class of medications primarily prescribed to reduce stomach acid production. They are invaluable in managing conditions like gastroesophageal reflux disease (GERD), peptic ulcers and Zollinger-Ellison syndrome. PPIs block the proton pumps in the stomach lining, thereby lowering the amount of acid produced. It alleviates symptoms such as heartburn, acid reflux and indigestion, promoting healing and preventing further damage to the oesophagus and stomach lining. PPIs are generally safe, but prolonged or inappropriate use can lead to potential side effects and nutrient deficiencies. Individuals must use PPIs under medical supervision, tailoring their usage to their specific conditions and needs.